Trifluoroacetic acid → HCID 9855936, compound

HRID 2251463Notes

Reaction equation

HRID 2251463 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([N:9]2[C@H:16]3[C@H:11]([CH2:12][CH2:13][N:14](C(OC(C)(C)C)=O)[CH2:15]3)[CH2:10]2)[CH:6]=[N:7][CH:8]=1.FC(F)(F)C(O)=O>>[CH3:1][O:2][C:3]1[CH:4]=[C:5]([N:9]2[C@H:16]3[C@H:11]([CH2:12][CH2:13][NH:14][CH2:15]3)[CH2:10]2)[CH:6]=[N:7][CH:8]=1

Participants

3

Reactant 2

HCID 6422Trifluoroacetic acidHCID 66757213HCID 66757213, compound

Product 1

HCID 9855936HCID 9855936, compoundYield 91.2%

Procedure

The product of Example 88A (0.540 g, 1.70 mmol) and trifluoroacetic acid were processed according to the procedure described in Example 64C to provide the title compound (0.340 g, 1.55 mmol, 91% yield).

Sources & evidence

ORD record
ord-f38d7ae0d16940eeb0d7edad3a0c8cfe
Source dataset
uspto-grants-2008_01
Patent number
US07319106B2

Reaction notes

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