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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2251547Generated: October 26, 2026

Propanoic acid, 2-bromo-2-methyl-, ethyl ester → 2-[3-(3-{(5-Isopropylpyridin-2-yl)[4-(trifluoromethoxy)benzyl]amino}propyl)phenoxy]-2-methylpropanoic acid

https://huagongshe.com/reaction/2251547

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPropanoic acid, 2-bromo-2-methyl-, ethyl esterHCID 11745—
Reactant3-(3-{(5-Isopropylpyridin-2-yl)[4-(trifluoromethoxy)benzyl]amino}propyl)phenolHCID 59643168—
Product2-[3-(3-{(5-Isopropylpyridin-2-yl)[4-(trifluoromethoxy)benzyl]amino}propyl)phenoxy]-2-methylpropanoic acidHCID 59643349—

Reaction Steps

Similarly prepared by alkylation of 3-(3-{(5-isopropylpyridin-2-yl)[4-(trifluoromethoxy)benzyl]amino}propyl)phenol with ethyl-2-bromo-isobutyrate followed by standard base-mediated hydrolysis.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07319104B2
Source datasetuspto-grants-2008_01
ORD IDord-ff168f1c7afa4e61afa0bb6a62fb5b6b
Source noteuspto-grants-2008_01