HRID2251583

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID123440

Bromomethyl 2-methoxyphenyl ketone

C9H9BrO2

结构：CCOC(=O)C(C)(C)Oc1ccc(CCN(Cc2ccc(C(F)(F)F)cc2)C(N)=S)cc1

HCID59643246

未命名化合物

PRODUCTS

生成物

结构：COc1ccccc1-c1csc(N(CCc2ccc(OC(C)(C)C(=O)O)cc2)Cc2ccc(C(F)(F)F)cc2)n1

HCID59643158

未命名化合物

PROCEDURE

实验过程

Similarly prepared from ethyl 2-[4-(2-{(aminocarbonothioyl)[4-(trifluoromethyl)benzyl]amino}ethyl)phenoxy]-2-methylpropanoate and 2-methoxyphenacyl bromide.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-375879d3c8244ff8bc47249323bb6041
来源数据集: uspto-grants-2008_01
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07319104B2
来源说明: uspto-grants-2008_01

反应 SMILES

[NH2:1][C:2]([N:4]([CH2:22][C:23]1[CH:28]=[CH:27][C:26]([C:29]([F:32])([F:31])[F:30])=[CH:25][CH:24]=1)[CH2:5][CH2:6][C:7]1[CH:21]=[CH:20][C:10]([O:11][C:12]([CH3:19])([CH3:18])[C:13]([O:15]CC)=[O:14])=[CH:9][CH:8]=1)=[S:3].[CH3:33][O:34][C:35]1[CH:44]=[CH:43][CH:42]=[CH:41][C:36]=1[C:37](=O)[CH2:38]Br>>[CH3:33][O:34][C:35]1[CH:44]=[CH:43][CH:42]=[CH:41][C:36]=1[C:37]1[N:1]=[C:2]([N:4]([CH2:22][C:23]2[CH:24]=[CH:25][C:26]([C:29]([F:32])([F:30])[F:31])=[CH:27][CH:28]=2)[CH2:5][CH2:6][C:7]2[CH:8]=[CH:9][C:10]([O:11][C:12]([CH3:19])([CH3:18])[C:13]([OH:15])=[O:14])=[CH:20][CH:21]=2)[S:3][CH:38]=1