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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2251583Generated: October 25, 2026

Bromomethyl 2-methoxyphenyl ketone → 2-[4-(2-{[4-(2-Methoxyphenyl)-1,3-thiazol-2-yl][4-(trifluoromethyl)benzyl]amino}ethyl)phenoxy]-2-methylpropanoic acid

https://huagongshe.com/reaction/2251583

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBromomethyl 2-methoxyphenyl ketoneHCID 123440—
ReactantEthyl 2-[4-(2-{(aminocarbonothioyl)[4-(trifluoromethyl)benzyl]amino}ethyl)phenoxy]-2-methylpropanoateHCID 59643246—
Product2-[4-(2-{[4-(2-Methoxyphenyl)-1,3-thiazol-2-yl][4-(trifluoromethyl)benzyl]amino}ethyl)phenoxy]-2-methylpropanoic acidHCID 59643158—

Reaction Steps

Similarly prepared from ethyl 2-[4-(2-{(aminocarbonothioyl)[4-(trifluoromethyl)benzyl]amino}ethyl)phenoxy]-2-methylpropanoate and 2-methoxyphenacyl bromide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07319104B2
Source datasetuspto-grants-2008_01
ORD IDord-375879d3c8244ff8bc47249323bb6041
Source noteuspto-grants-2008_01