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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2251585Generated: October 26, 2026

p-Chlorophenacyl bromide → 2-[4-(2-{[4-(4-Chlorophenyl)-1,3-thiazol-2-yl][4-(trifluoromethyl)benzyl]amino}ethyl)phenoxy]-2-methylpropanoic acid

https://huagongshe.com/reaction/2251585

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-Chlorophenacyl bromideHCID 68303—
ReactantEthyl 2-[4-(2-{(aminocarbonothioyl)[4-(trifluoromethyl)benzyl]amino}ethyl)phenoxy]-2-methylpropanoateHCID 59643246—
Product2-[4-(2-{[4-(4-Chlorophenyl)-1,3-thiazol-2-yl][4-(trifluoromethyl)benzyl]amino}ethyl)phenoxy]-2-methylpropanoic acidHCID 59643166—

Reaction Steps

Similarly prepared from ethyl 2-[4-(2-{(aminocarbonothioyl)[4-(trifluoromethyl)benzyl]amino}ethyl)phenoxy]-2-methylpropanoate and 4-chlorophenacyl bromide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07319104B2
Source datasetuspto-grants-2008_01
ORD IDord-25a33ff172504f03ac00eb3d60472e22
Source noteuspto-grants-2008_01