HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 2,3-bis-benzyloxy-5-trifluoromethyl-benzoate → Methyl 2,3-dihydroxy-5-trifluoromethyl-benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 2,3-bis-benzyloxy-5-trifluoromethyl-benzoate | HCID 59642996 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | Methyl 2,3-dihydroxy-5-trifluoromethyl-benzoate | HCID 59643027 | — |
Reaction Steps
To a solution of methyl 2,3-bis-benzyloxy-5-trifluoromethyl-benzoate (280 mg, 0.67 mmol) in 10 mL MeOH, Pd/C (10%, 30 mg) was added and the mixture was stirred 16 h under a H2 atmosphere. The reaction mixture was then filtered through Celite and evaporated in vacuo to yield the title compound as a greyish solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07319101B2 |
| Source dataset | uspto-grants-2008_01 |
| ORD ID | ord-a946540104ad47819fefbeec3382bcac |
| Source note | uspto-grants-2008_01 |