HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,5-Dimethylisoxazole-4-boronic acid → 5-(3,5-Dimethylisoxazol-4-yl)-3,3-dimethylindan-1-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,5-Dimethylisoxazole-4-boronic acid | HCID 2734346 | — |
| Reactant | Trifluoromethanesulfonic acid 3,3-dimethyl-1-oxo-indan-5-yl ester | HCID 57618520 | — |
| Product | 5-(3,5-Dimethylisoxazol-4-yl)-3,3-dimethylindan-1-one | HCID 69038561 | — |
Reaction Steps
The title compound was prepared from trifluoro-methanesulfonic acid 3,3-dimethyl-1-oxo-indan-5-yl ester and 3,5-dimethylisoxazole-4-boronic acid according to the coupling procedure described in example 21. MS m/z 256; HRMS: calcd for C16H17NO2+H+, 256.13321; found (ESI, [M+H]+), 256.1343.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07319152B2 |
| Source dataset | uspto-grants-2008_01 |
| ORD ID | ord-41aa709aaed0408a98e46d1eba55761d |
| Source note | uspto-grants-2008_01 |