HuagongsheHuagongshe Chemistry Print Report · For research reference only
(3-Cyano-5-fluorophenyl)boronic acid → 3-(3,3-dimethyl-1-oxo-2,3-dihydro-1H-inden-5-yl)-5-fluorobenzonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (3-Cyano-5-fluorophenyl)boronic acid | HCID 23435605 | — |
| Reactant | Trifluoromethanesulfonic acid 3,3-dimethyl-1-oxo-indan-5-yl ester | HCID 57618520 | — |
| Product | 3-(3,3-dimethyl-1-oxo-2,3-dihydro-1H-inden-5-yl)-5-fluorobenzonitrile | HCID 69037949 | — |
Reaction Steps
The title compound was prepared from trifluoro-methanesulfonic acid 3,3-dimethyl-1-oxo-indan-5-yl ester and 3-cyano-5-fluorophenyl boronic acid according to the procedure described in example 21. MS (ES) m/z 280.1; HRMS: calcd for C18H14FNO+H+, 280.11322; found (ESI, [M+H]+), 280.1129.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07319152B2 |
| Source dataset | uspto-grants-2008_01 |
| ORD ID | ord-c3f628d4768847b698ce909c51efd8ef |
| Source note | uspto-grants-2008_01 |