HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → 1-Bromo-4-(1,1-dimethoxyethyl)benzene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | p-Bromoacetophenone | HCID 7466 | — |
| Reactant | Trimethyl orthoformate | HCID 9005 | — |
| Product | 1-Bromo-4-(1,1-dimethoxyethyl)benzene | HCID 10911782 | — |
Reaction Steps
A mixture of 2 g (0.01 mole) of 4-bromoacetophenone, 5.6 ml of trimethyl orthoformate, 5.6 ml of methanol and 0.67 g of Amberlite® IR 120 is refluxed for three hours. After cooling, it is filtered through, Celite® and the filtered solution is evaporated. 2.4 g of the title product are obtained as an oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07320982B2 |
| Source dataset | uspto-grants-2008_01 |
| ORD ID | ord-cf6ace7e8a934a98bcd149c796d6c813 |
| Source note | uspto-grants-2008_01 |