Ether hydrochloride → (R)-7-Chloro-5,11-dihydro-5-[1-(3,4-methylenedioxyphenethyl)pyrrolidin-2-ylmethyl]dibenzo[b,e][1,4]oxazepine hydrochloride

Participants

Reaction Steps

3.0 ml of 2 M hydrogen chloride/diethyl ether was added to a solution of (R)-7-chloro-5,11-dihydro-5-[1-(3,4-methylenedioxyphenethyl)pyrrolidin-2-ylmethyl]dibenzo[b,e][1,4]oxazepine (0.63 g) in dichloromethane (5 ml), and they were stirred together for 2 hours. The solvent was evaporated under reduced pressure. The obtained residue was stirred in hexane to obtain the title compound in the form of a light brown solid (348 mg, 89%).

Provenance & Evidence