Oxalyl chloride → HCID 53853898, compound

HRID 2251918Notes

Reaction equation

HRID 2251918 reaction equation
[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([CH:7]=[CH:8][C:9]([OH:11])=O)[CH:2]=1.C(Cl)(=O)C(Cl)=O.[C:18]1([CH:24]([C:33]2[CH:38]=[CH:37][CH:36]=[CH:35][CH:34]=2)[CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][NH2:32])[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1>>[C:33]1([CH:24]([C:18]2[CH:19]=[CH:20][CH:21]=[CH:22][CH:23]=2)[CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][NH:32][C:9](=[O:11])[CH:8]=[CH:7][C:3]2[CH:2]=[N:1][CH:6]=[CH:5][CH:4]=2)[CH:34]=[CH:35][CH:36]=[CH:37][CH:38]=1

Participants

4

Reactant 3

HCID 65578Oxalyl chlorideHCID 1019843-(3-Pyridinyl)-2-propenoic acidHCID 17940752HCID 17940752, compound

Product 1

HCID 53853898HCID 53853898, compound

Procedure

Batch size: 2.7 g (18.0 mmol) 3-(3-pyridyl)-acrylic acid, 5 ml (57.9 mmol) oxalyl chloride, 3.9 ml (28.0 mmol) TEA and 4.0 g (14,0 mmol) 8,8-diphenyloctylamine.

Sources & evidence

ORD record
ord-e299763b43fc4fc591152164e09b1fc0
Source dataset
uspto-grants-2008_01
Patent number
US07320993B1

Reaction notes

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