Oxalyl chloride → HCID 68502999, compound

HRID 2251921Notes

Reaction equation

HRID 2251921 reaction equation
[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([CH:7]=[CH:8][C:9]([OH:11])=O)[CH:2]=1.C(Cl)(=O)C(Cl)=O.[CH2:18]1[C:27]2[C:22]3[C:23](=[CH:28][CH:29]=[CH:30][C:21]=3[CH2:20][N:19]1[CH2:31][CH2:32][CH2:33][CH2:34][NH2:35])[CH:24]=[CH:25][CH:26]=2>>[CH2:18]1[C:27]2[C:22]3[C:23](=[CH:28][CH:29]=[CH:30][C:21]=3[CH2:20][N:19]1[CH2:31][CH2:32][CH2:33][CH2:34][NH:35][C:9](=[O:11])[CH:8]=[CH:7][C:3]1[CH:2]=[N:1][CH:6]=[CH:5][CH:4]=1)[CH:24]=[CH:25][CH:26]=2

Participants

4

Reactant 3

HCID 65578Oxalyl chlorideHCID 1019843-(3-Pyridinyl)-2-propenoic acidHCID 54417824HCID 54417824, compound

Product 1

HCID 68502999HCID 68502999, compound

Procedure

Batch size: 1.8 g (12.1 mmol) 3-(3-pyridyl)-acrylic acid, 4.0 g (31.5 mmol) oxalyl chloride and 2.6 g (10.8 mmol) 4-(1H,3H-benzo[de]isoquinolin-2-yl)-butylamine.

Sources & evidence

ORD record
ord-745b101309c14f939b504d0233747386
Source dataset
uspto-grants-2008_01
Patent number
US07320993B1

Reaction notes

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