Oxalyl chloride → HCID 57166640, compound

HRID 2251931Notes

Reaction equation

HRID 2251931 reaction equation
[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([CH:7]=[CH:8][C:9]([OH:11])=O)[CH:2]=1.C(Cl)(=O)C(Cl)=O.[CH:18]([N:31]([CH3:41])[CH2:32][CH2:33][N:34]([CH3:40])[CH2:35][CH2:36][CH2:37][CH2:38][NH2:39])([C:25]1[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=1)[C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1>>[CH:18]([N:31]([CH3:41])[CH2:32][CH2:33][N:34]([CH3:40])[CH2:35][CH2:36][CH2:37][CH2:38][NH:39][C:9](=[O:11])[CH:8]=[CH:7][C:3]1[CH:2]=[N:1][CH:6]=[CH:5][CH:4]=1)([C:25]1[CH:26]=[CH:27][CH:28]=[CH:29][CH:30]=1)[C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1

Participants

4

Reactant 3

HCID 65578Oxalyl chlorideHCID 1019843-(3-Pyridinyl)-2-propenoic acidHCID 57156999HCID 57156999, compound

Product 1

HCID 57166640HCID 57166640, compound

Procedure

Batch size: 5.5 g (36.8 mmol) 3-(3-pyridyl)-acrylic acid, 12.7 g (100.0 mmol) oxalyl chloride and 10.9 g (33.5 mmol) 4-([2-(benzhydryl-methyl-amino)-ethyl]-methyl-amino)-butylamine.

Sources & evidence

ORD record
ord-a27132898dfb45a784d621905b39af59
Source dataset
uspto-grants-2008_01
Patent number
US07320993B1

Reaction notes

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