Hydrazine hydrate (1:1) → 4-(4,5-Diphenylimidazol-1-yl)-butylamine

HRID 2251944Notes

Reaction equation

HRID 2251944 reaction equation
[C:1]1([C:7]2[N:8]=[CH:9][N:10]([CH2:18][CH2:19][CH2:20][CH2:21][N:22]3C(=O)C4C(=CC=CC=4)C3=O)[C:11]=2[C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.O.NN>C(O)C>[C:1]1([C:7]2[N:8]=[CH:9][N:10]([CH2:18][CH2:19][CH2:20][CH2:21][NH2:22])[C:11]=2[C:12]2[CH:13]=[CH:14][CH:15]=[CH:16][CH:17]=2)[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

Participants

4

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 102239732-[4-(4,5-Diphenylimidazol-1-yl)-butyl]-isoindol-1,3-dione

Product 1

HCID 99658394-(4,5-Diphenylimidazol-1-yl)-butylamine

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Batch size: 14.0 g (33.2 mmol) 2-[4-(4,5-diphenyl-imidazol-1-yl)-butyl]-isoindol-1,3-dione and 3.3 ml (66.4 mmol) hydrazine hydrate in 130 ml ethanol.

Sources & evidence

ORD record
ord-5b8f45f585694c9cb9418bc7f54a16c8
Source dataset
uspto-grants-2008_01
Patent number
US07320993B1

Reaction notes

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