Hydrazine hydrate (1:1) → 5-Hydroxy-5,5-diphenyl-pentylamine

HRID 2251946Notes

Reaction equation

HRID 2251946 reaction equation
[OH:1][C:2]([C:24]1[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1)([C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1)[CH2:3][CH2:4][CH2:5][CH2:6][N:7]1C(=O)C2C(=CC=CC=2)C1=O.O.NN>C(O)C>[OH:1][C:2]([C:24]1[CH:25]=[CH:26][CH:27]=[CH:28][CH:29]=1)([C:18]1[CH:19]=[CH:20][CH:21]=[CH:22][CH:23]=1)[CH2:3][CH2:4][CH2:5][CH2:6][NH2:7]

Participants

4

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 17940746HCID 17940746, compound

Product 1

HCID 179407425-Hydroxy-5,5-diphenyl-pentylamine

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Batch size: 5.0 g (13.0 mmol) 2-(5-hydroxy-5,5-diphenyl-pentyl)-isoindol-1,3-dione and 1.3 g (26.0 mmol) hydrazine hydrate in 50 ml ethanol.

Sources & evidence

ORD record
ord-2e2faca570c348639acc514b8181acf2
Source dataset
uspto-grants-2008_01
Patent number
US07320993B1

Reaction notes

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