Hydrochloric Acid → 4-(Benzhydryl-amino)-butylamine

HRID 2251950Notes

Reaction equation

HRID 2251950 reaction equation
C(OC(=O)[NH:7][CH2:8][CH2:9][CH2:10][CH2:11][NH:12][CH:13]([C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1)[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1)(C)(C)C.Cl>CO>[CH:13]([NH:12][CH2:11][CH2:10][CH2:9][CH2:8][NH2:7])([C:20]1[CH:21]=[CH:22][CH:23]=[CH:24][CH:25]=1)[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 53775424N-[4-(benzhydryl-amino)-butyl]-carbamic acid tert-butyl ester

Product 1

HCID 124911934-(Benzhydryl-amino)-butylamine

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

Batch size: 4.6 g (<11.3 mmol) N-[4-(benzhydryl-amino)-butyl]-carbamic acid tert-butyl ester and 5.2 ml (63 mmol) concentrated hydrochloric acid in 50 methanol.

Sources & evidence

ORD record
ord-74bc526abee44844a1bcd63a19f219c9
Source dataset
uspto-grants-2008_01
Patent number
US07320993B1

Reaction notes

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