Hydrazine hydrate (1:1) → HCID 57156999, compound

HRID 2251953Notes

Reaction equation

HRID 2251953 reaction equation
[CH:1]([N:14]([CH3:34])[CH2:15][CH2:16][N:17]([CH3:33])[CH2:18][CH2:19][CH2:20][CH2:21][N:22]1C(=O)C2C(=CC=CC=2)C1=O)([C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.NN.O>C(O)C>[CH:1]([N:14]([CH3:34])[CH2:15][CH2:16][N:17]([CH3:33])[CH2:18][CH2:19][CH2:20][CH2:21][NH2:22])([C:8]1[CH:9]=[CH:10][CH:11]=[CH:12][CH:13]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

4

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 57037785HCID 57037785, compound

Product 1

HCID 57156999HCID 57156999, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Batch size: 20.8 g (45.6 mmol) 2-(4-{[2-(benzhydryl-methyl-amino)-ethyl]-methylamino}-butyl)-isoindol-1,3-dione and 4.6 g (91.9 mmol) hydrazine.hydrate in 200 ml ethanol.

Sources & evidence

ORD record
ord-6dcaf86b62e44a1e8426991cfceb003c
Source dataset
uspto-grants-2008_01
Patent number
US07320993B1

Reaction notes

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