HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzenesulfonamide, 4-(hydroxymethyl)-N-methyl- → 4-Formyl-N-methylbenzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzenesulfonamide, 4-(hydroxymethyl)-N-methyl- | HCID 17981768 | — |
| Catalyst | HCID 178418406 | HCID 178418406 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 4-Formyl-N-methylbenzenesulfonamide | HCID 14327177 | 40% |
Reaction Steps
Add 4-hydroxymethyl-N-methyl-benzenesulfonamide (0.28 g) to a mixture of manganese dioxide (2.8 g) in 20 mL of dichloromethane. Stir at room temperature overnight and filter over Celite®. Concentrate under reduced pressure to provide (0.11 g, 40%) of the title compound as oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07320995B2 |
| Source dataset | uspto-grants-2008_01 |
| ORD ID | ord-5cf1aa6e9efb48628714e27476dcb4b5 |
| Source note | uspto-grants-2008_01 |