Thionyl Chloride → bis(4-methoxyphenyl)chloromethane

HRID 2252250Notes

Reaction equation

HRID 2252250 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([CH:9]([C:11]2[CH:16]=[CH:15][C:14]([O:17][CH3:18])=[CH:13][CH:12]=2)O)=[CH:5][CH:4]=1.S(Cl)([Cl:21])=O>>[Cl:21][CH:9]([C:11]1[CH:16]=[CH:15][C:14]([O:17][CH3:18])=[CH:13][CH:12]=1)[C:6]1[CH:7]=[CH:8][C:3]([O:2][CH3:1])=[CH:4][CH:5]=1

Participants

3

Reactant 2

HCID 24386Thionyl ChlorideHCID 69768p,p'-Dimethoxybenzhydryl alcohol

Product 1

HCID 10706646bis(4-methoxyphenyl)chloromethane

Procedure

Bis(4-methoxyphenyl)methanol (30 g) was treated with thionyl chloride (40 mL). The resulting mixture was refluxed for 2.5 hours and concentrated to give the desired product.

Workup

  1. temperatureThe resulting mixture was refluxed for 2.5 hours
  2. concentrationconcentrated

Sources & evidence

ORD record
ord-6d59e8412476428fa6342a6116691eda
Source dataset
uspto-grants-2008_01
Patent number
US07320986B2

Reaction notes

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