Cyclopropanecarbonyl chloride → HCID 58585306, compound

HRID 2252281Notes

Reaction equation

HRID 2252281 reaction equation
[Cl:1][C:2]1[C:3](=[O:21])[N:4]([C:14]2[CH:19]=[CH:18][C:17]([Cl:20])=[CH:16][CH:15]=2)[N:5]=[CH:6][C:7]=1[N:8]1[CH2:13][CH2:12][NH:11][CH2:10][CH2:9]1.[CH:22]1([C:25](Cl)=[O:26])[CH2:24][CH2:23]1>>[Cl:1][C:2]1[C:3](=[O:21])[N:4]([C:14]2[CH:15]=[CH:16][C:17]([Cl:20])=[CH:18][CH:19]=2)[N:5]=[CH:6][C:7]=1[N:8]1[CH2:9][CH2:10][N:11]([C:25]([CH:22]2[CH2:24][CH2:23]2)=[O:26])[CH2:12][CH2:13]1

Participants

3

Reactant 2

HCID 77637Cyclopropanecarbonyl chlorideHCID 58585369HCID 58585369, compound

Product 1

HCID 58585306HCID 58585306, compound

Procedure

Obtainable by general method 2 from 9.76 g (30.0 mmol) of the compound from Example 2A with 3.3 ml (36 mmol) of cyclopropylcarbonyl chloride.

Sources & evidence

ORD record
ord-b97faff2f6c649b095598e9962740655
Source dataset
uspto-grants-2008_01
Patent number
US07320977B2

Reaction notes

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