Pyridinium chloride → 3-[2-(3,5-Dihydroxy-4-i-propylphenyl)ethenyl]benzoic acid
Reaction equation
C[O:2][C:3]1[CH:4]=[C:5]([CH:14]=[CH:15][C:16]2[CH:17]=[C:18]([CH:22]=[CH:23][CH:24]=2)[C:19]([OH:21])=[O:20])[CH:6]=[C:7]([O:12]C)[C:8]=1[CH:9]([CH3:11])[CH3:10].Cl.N1C=CC=CC=1>>[OH:2][C:3]1[CH:4]=[C:5]([CH:14]=[CH:15][C:16]2[CH:17]=[C:18]([CH:22]=[CH:23][CH:24]=2)[C:19]([OH:21])=[O:20])[CH:6]=[C:7]([OH:12])[C:8]=1[CH:9]([CH3:11])[CH3:10]Participants
3
Procedure
This material was prepared from 3-[2-(3,5-dimethoxy-4-i-propylphenyl)ethenyl]benzoic acid 2B and pyridine hydrochloride in 86% yield in the same way as described in example 3. 1HNMR (DMSO-d6, ppm): δ 1.22 (d, J=7.0 Hz, 6H), 6.48 (s, 2H), 7.03 (d, J=17 Hz, 1H), 7.12 (d, J=17 Hz, 1H), 7.46 (t, J=7.5 Hz, 1H), 7.7-7.9 (m, 2H), 8.06 (s, 1H), 9.12 (s, 2H).
Sources & evidence
- ORD record
- ord-147ced80c6184905a5df4294c21c25db
- Source dataset
- uspto-grants-2008_01
- Patent number
- US07321050B2
Reaction notes
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