反应详情

A mixture of 3.35 g. of 7-(α,α,α-trifluoro-m-tolyl)pyrazolo[1,5-a]pyrimidine-3-carboxylic acid ethyl ester, 20 ml. of 5 N sodium hydroxide and 75 ml. of ethanol is heated on a steam bath for 4 hours. The mixture is cooled and solid is recovered by filtration giving the desired product, m.p. 322°-325° C. (dec.).

1. additionA mixture of 3.35 g
2. temperatureThe mixture is cooled
3. filtrationsolid is recovered by filtration