Triethylamine → HCID 69117559, compound

HRID 2252455Notes

Reaction equation

HRID 2252455 reaction equation
C(N(CC)CC)C.C([O:11][C@@H:12]1[O:29][C@H:28]([CH2:30][O:31][C:32]2[CH:37]=[CH:36][CH:35]=[C:34]([Br:38])[CH:33]=2)[C@@H:23]([O:24]C(=O)C)[C@H:18]([O:19]C(=O)C)[C@H:13]1[O:14]C(=O)C)(=O)C.CO.O>C(OCC)(=O)C.ClCCl>[Br:38][C:34]1[CH:33]=[C:32]([O:31][CH2:30][C@H:28]2[O:29][C@@H:12]([OH:11])[C@H:13]([OH:14])[C@@H:18]([OH:19])[C@@H:23]2[OH:24])[CH:37]=[CH:36][CH:35]=1

Participants

5

Reactant 3

HCID 8471TriethylamineHCID 22242641Methanol--water (1/1)HCID 69257541HCID 69257541, compound

Product 1

HCID 69117559HCID 69117559, compound

Reagents, catalysts & solvents 1

HCID 21226138Dichloromethane ethylacetateSolvent

Procedure

Triethylamine (1 mL) was added at room temperature to 1,2,3,4-tetra-O-acetyl-6-O-(3-bromophenyl)-β-D-glucopyranose (200 mg, 0.40 mmol) dissolved in 5: I methanol-water (6 mL). The reaction progress was monitored by LCMS and TLC (20% ethyl acetate-dichloromethane). Upon completion, the solvents were removed in vacuo to afford 6-O-(3-bromophenyl)-β-D-glucopyranose which was carried on without further purification.

Workup

  1. dissolutiondissolved in 5
  2. customUpon completion, the solvents were removed in vacuo

Sources & evidence

ORD record
ord-3e5d01bb738941d0b40faed731a1a667
Source dataset
uspto-grants-2008_01
Patent number
US07320972B2

Reaction notes

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