反应详情

A solution of 0.01 mole of 7-(α,α,α-trifluoro-m-tolyl)pyrazolo[1,5-a]pyrimidine-3-carboxylic acid in tetrahydrofuran is added dropwise to a chilled (0° C.) solution of 0.02 mole of diborane in tetrahydrofuran. After standing overnight the mixture is poured onto ice and the product extracted into dichloromethane. The dichloromethane layer is washed with water, dried (MgSO4) and the solvent removed to give the product of the example.

1. additionthe mixture is poured onto ice
2. extractionthe product extracted into dichloromethane
3. washThe dichloromethane layer is washed with water
4. dry with materialdried (MgSO4)
5. customthe solvent removed
6. customto give the product of the example