Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 225290Generated: October 25, 2026

Pyrazole, 3-amino-4-cyano-5-ethyl- → 2-Ethyl-7-(alpha,alpha,alpha-trifluoro-m-tolyl)pyrazolo[1,5-a]pyrimidine-3-carbonitrile

https://huagongshe.com/reaction/225290

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPyrazole, 3-amino-4-cyano-5-ethyl-HCID 114021—
Reactant3-Dimethylamino-3'-trifluoromethylacrylophenoneHCID 730024—
Product2-Ethyl-7-(alpha,alpha,alpha-trifluoro-m-tolyl)pyrazolo[1,5-a]pyrimidine-3-carbonitrileHCID 23329837—

Reaction Steps

As for Example 1, 3-amino-5-ethylpyrazole-4-carbonitrile is reacted with 3-dimethylamino-3'-(trifluoromethyl)acrylophenone to give the product as crystals, m.p. 144°-146° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04236005
Source datasetuspto-grants-1980_11
ORD IDord-6445dbd81c5d4434a10a89c831583498
Source noteuspto-grants-1980_11