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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 225293Generated: October 29, 2026

3-(Dimethylamino)-1-[2-(trifluoromethyl)phenyl]prop-2-en-1-one → Ethyl 7-(alpha,alpha,alpha-trifluoro-o-tolyl)pyrazolo[1,5-a]pyrimidine-3-carboxylate

https://huagongshe.com/reaction/225293

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(Dimethylamino)-1-[2-(trifluoromethyl)phenyl]prop-2-en-1-oneHCID 54259832—
ReactantHCID 178469928HCID 178469928—
ProductEthyl 7-(alpha,alpha,alpha-trifluoro-o-tolyl)pyrazolo[1,5-a]pyrimidine-3-carboxylateHCID 23329868—

Reaction Steps

As for Example 1, ethyl 3-aminopyrazole-4-carboxylate is reacted with 3-dimethylamino-2'-(trifluoromethyl)acrylophenone to give the product as crystals, m.p. 148°-149° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04236005
Source datasetuspto-grants-1980_11
ORD IDord-12557a5efb6f429cb75670b4a2ddc1b9
Source noteuspto-grants-1980_11