Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2252969Generated: November 1, 2026

Hydrochloric Acid → 4-Bromo-2-{[(2R)-morpholin-2-yl]methyl}phenol

https://huagongshe.com/reaction/2252969

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantN-Boc-(R)-2-(5-bromo-2-hydroxybenzyl)morpholineHCID 58689695—
Product4-Bromo-2-{[(2R)-morpholin-2-yl]methyl}phenolHCID 58689709—

Reaction Steps

Deprotection of N-Boc-(R)-2-(5-bromo-2-hydroxybenzyl)morpholine, using hydrogen chloride (4M, in methanol), afforded the morpholine example 1 as an off-white solid (51 mg, 100%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07323466B2
Source datasetuspto-grants-2008_01
ORD IDord-afc4bd7fa5534e3686f9306bdd5ffc8d
Source noteuspto-grants-2008_01