HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Chloroethyl chloroformate → 2-(4-Fluoro-3-methylbenzyl)-morpholine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Chloroethyl chloroformate | HCID 521305 | — |
| Reactant | N-benzyl-2-(4-fluoro-3-methylbenzyl)-morpholine | HCID 67073266 | — |
| Reactant | N-Boc-(R)-2-(3-(2-(3-pyridinyl)vinyl)-benzyl)morpholine | HCID 67073511 | — |
| Product | 2-(4-Fluoro-3-methylbenzyl)-morpholine | HCID 11644158 | — |
Reaction Steps
Example 71 was prepared as described for example 27, but using N-benzyl-2-(4-fluoro-3-methylbenzyl)-morpholine, intermediate (a) and 1-chloroethyl chloroformate. Example 71 was isolated as a colorless oil (13.7 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07323466B2 |
| Source dataset | uspto-grants-2008_01 |
| ORD ID | ord-89dcdeaa3dc7442bad80c7b77db87e1a |
| Source note | uspto-grants-2008_01 |