HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(Bromomethyl)-1-fluoro-2-methylbenzene → N-benzyl-2-(4-fluoro-3-methylbenzyl)-morpholin-3-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(Bromomethyl)-1-fluoro-2-methylbenzene | HCID 2778135 | — |
| Reactant | 4-Benzylmorpholin-3-one | HCID 12294087 | — |
| Reactant | N-Boc-(R)-2-(3-(hydroxymethyl)benzyl)morpholine | HCID 67073062 | — |
| Product | N-benzyl-2-(4-fluoro-3-methylbenzyl)-morpholin-3-one | HCID 67073536 | — |
Reaction Steps
N-Benzyl-2-(4-fluoro-3-methylbenzyl)-morpholin-3-one was prepared as described for example 70, intermediate (b), but using 4-benzylmorpholine-3-one and 4-fluoro-3-methylbenzyl bromide and was isolated as a pale yellow oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07323466B2 |
| Source dataset | uspto-grants-2008_01 |
| ORD ID | ord-485fe7f3d039470899e552073c84c308 |
| Source note | uspto-grants-2008_01 |