HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Chloroethyl chloroformate → Morpholine, 2-[[2-(difluoromethoxy)phenyl]methyl]-
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Chloroethyl chloroformate | HCID 521305 | — |
| Reactant | N-benzyl-2-(2-difluoromethoxy-benzyl)-morpholine | HCID 67073057 | — |
| Reactant | N-Boc-(R)-2-(3-(2-(3-pyridinyl)vinyl)-benzyl)morpholine | HCID 67073511 | — |
| Product | Morpholine, 2-[[2-(difluoromethoxy)phenyl]methyl]- | HCID 11601200 | — |
Reaction Steps
Example 75 was prepared as described for example 27, but using N-benzyl-2-(2-difluoromethoxy-benzyl)-morpholine, intermediate (a) and 1-chloroethyl chloroformate and example 75 was isolated as a colorless oil (7.9 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07323466B2 |
| Source dataset | uspto-grants-2008_01 |
| ORD ID | ord-eb80db0ab7d14f9cb5a3f21b3d45bb18 |
| Source note | uspto-grants-2008_01 |