N,N-Dimethylethylenediamine → HCID 11348719, compound

HRID 2253122Notes

Reaction equation

HRID 2253122 reaction equation
C(O[C:6]([C:8]1[N:9]=[C:10]([Cl:23])[C:11]2[C:16]([C:17]=1[OH:18])=[CH:15][C:14]([O:19][CH:20]([CH3:22])[CH3:21])=[CH:13][CH:12]=2)=[O:7])CCC.[CH3:24][N:25]([CH3:29])[CH2:26][CH2:27][NH2:28]>>[CH3:24][N:25]([CH3:29])[CH2:26][CH2:27][NH:28][C:6]([C:8]1[N:9]=[C:10]([Cl:23])[C:11]2[C:16]([C:17]=1[OH:18])=[CH:15][C:14]([O:19][CH:20]([CH3:21])[CH3:22])=[CH:13][CH:12]=2)=[O:7]

Participants

3

Reactant 2

HCID 66053N,N-DimethylethylenediamineHCID 18698144HCID 18698144, compound

Product 1

HCID 11348719HCID 11348719, compound

Procedure

Synthesized from 1-chloro-4-hydroxy-6-isopropoxy-isoquinoline-3-carboxylic acid butyl ester (can be obtained according to U.S. Pat. No. 6,093,730, October 1998, Weidmann et al.) and N,N-dimethyl-ethane-1,2-diamine in analogy to example B-4, followed by deprotection in analogy to example B-1 f); MS-(+)-ion: M+1=352.1.

Workup

  1. customcan be obtained

Sources & evidence

ORD record
ord-3e8a024c91434aa1ae02befd516a0f53
Source dataset
uspto-grants-2008_01
Patent number
US07323475B2

Reaction notes

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