1-Propanol → HCID 11344952, compound

HRID 2253248Notes

Reaction equation

HRID 2253248 reaction equation
[CH:1]1([C:12]([OH:14])=[O:13])[CH2:6][CH2:5][CH:4]2[C:7]([O:9][C:10](=[O:11])[CH:3]2[CH2:2]1)=[O:8].C([OH:18])CC>>[CH:1]1([C:12]([OH:14])=[O:13])[CH2:6][CH2:5][CH:4]([C:7]([OH:18])=[O:8])[CH:3]([C:10]([OH:9])=[O:11])[CH2:2]1

Participants

3

Reactant 2

HCID 10311-PropanolHCID 156855011,3-Dioxooctahydroisobenzofuran-5-carboxylic acid

Product 1

HCID 11344952HCID 11344952, compound

Procedure

Into a four-necked flask equipped with a thermometer, a stirring device, a condenser and a temperature controller, 198 parts by weight of cyclohexane-1,3,4-tricarboxylic 3,4-anhydride and 300 parts by weight of n-propyl alcohol were charged and allowed to react at 100° C. for 3 h. After the reaction, the excess n-propyl alcohol was distilled off under reduced pressure to obtain monopropyl ester of cyclohexane-1,3,4-tricarboxylic acid as a colorless and transparent liquid. The product was identified by confirming the disappearance of the characteristic absorption of acid anhydride group (1850 and 1790 cm−1) and the appearance of the characteristic absorption of ester group (1735 cm−1) on infrared absorption spectra, and by determining the molecular weight using a gas chromatograph-mass spectrometer.

Workup

  1. customInto a four-necked flask equipped with a thermometer
  2. customto react at 100° C. for 3 h
  3. customAfter the reaction
  4. distillationthe excess n-propyl alcohol was distilled off under reduced pressure

Sources & evidence

ORD record
ord-3775b84eddd24e75b0a9dee3ba5cfc52
Source dataset
uspto-grants-2008_01
Patent number
US07323522B2

Reaction notes

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