Methyl Acrylate → HCID 58633262, compound

HRID 2253446Notes

Reaction equation

HRID 2253446 reaction equation
[C:1]1([C:7]2[CH2:8][O:9][C:10]3[C:15]([C:16]=2[C:17]2[CH:22]=[CH:21][C:20](OS(C(F)(F)F)(=O)=O)=[CH:19][CH:18]=2)=[CH:14][CH:13]=[CH:12][CH:11]=3)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[C:31]([O:35][CH3:36])(=[O:34])[CH:32]=[CH2:33]>CC#N>[CH3:36][O:35][C:31](=[O:34])[CH:32]=[CH:33][C:20]1[CH:19]=[CH:18][C:17]([C:16]2[C:15]3[C:10](=[CH:11][CH:12]=[CH:13][CH:14]=3)[O:9][CH2:8][C:7]=2[C:1]2[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=2)=[CH:22][CH:21]=1

Participants

4

Reactant 2

HCID 7294Methyl AcrylateHCID 23573352HCID 23573352, compound

Product 1

HCID 58633262HCID 58633262, compound

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Procedure

Prepared by the Heck coupling of 3b and methyl acrylate in accordance with the general method described in Example IV. Yield (94%); APcI m/z: 410 (M+H+CH3CN+, 100%).

Workup

  1. customYield (94%)

Sources & evidence

ORD record
ord-1bd3c19f3ba74813a62c3b9d3467c4b3
Source dataset
uspto-grants-2008_01
Patent number
US07323587B2

Reaction notes

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