Hydrogen Bromide → HCID 19746156, compound

HRID 2253657Notes

Reaction equation

HRID 2253657 reaction equation
[O:1]([C:8]1[CH:9]=[N:10][CH:11]=[CH:12][CH:13]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[BrH:14]>C(O)C>[BrH:14].[O:1]([C:8]1[CH:9]=[N:10][CH:11]=[CH:12][CH:13]=1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

4

Reactant 2

HCID 260Hydrogen BromideHCID 2005103-Phenoxypyridine

Product 1

HCID 19746156HCID 19746156, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A solution of 85 g. of 3-phenoxypyridine in 100 ml. of absolute ethanol is treated with 84 g. of 48% hydrobromic acid with stirring and the solution is evaporated to dryness at reduced pressure. The residue is dissolved in warm 2-propanol, the solution is diluted to cloudiness with ether and chilled to crystallize 3-phenoxypyridine hydrobromide; m.p. 132°-134° C. after drying at reduced pressure.

Workup

  1. customthe solution is evaporated to dryness at reduced pressure
  2. dissolutionThe residue is dissolved in warm 2-propanol
  3. additionthe solution is diluted to cloudiness with ether
  4. temperaturechilled
  5. customto crystallize 3-phenoxypyridine hydrobromide
  6. customm.p. 132°-134° C. after drying at reduced pressure

Sources & evidence

ORD record
ord-cfaf43e7398c4ddea9fc3e423ab53ba0
Source dataset
uspto-grants-1993_08
Patent number
US05232934

Reaction notes

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