Hydrochloric Acid → HCID 9930208, compound

HRID 2253929Notes

Reaction equation

HRID 2253929 reaction equation
[C:1]([C:5]([CH3:28])([CH3:27])[CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][C:17]([OH:26])([CH2:22][C:23]([OH:25])=[O:24])[CH2:18][C:19]([OH:21])=[O:20])([O:3]C)=[O:2].Cl>[OH-].[Na+]>[C:1]([C:5]([CH3:28])([CH3:27])[CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][C:17]([OH:26])([CH2:22][C:23]([OH:25])=[O:24])[CH2:18][C:19]([OH:21])=[O:20])([OH:3])=[O:2]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 19746855HCID 19746855, compound

Product 1

HCID 9930208HCID 9930208, compound

Reagents, catalysts & solvents 1

HCID 14798Sodium HydroxideSolvent

Procedure

A 0.90 g sample of the product of Example 10 dissolved in 10 mL of 10% NaOH was heated at 50° overnight. The solution was made pH 2 with dilute HCl and extracted with ether which was dried (NH2SO4) and evaporated. The residue dissolved and CH2Cl2 was filtered, evaporated and dried at 30°/0.5 mm to give the title compound as a yellow glass, 0.90 g. A portion crystallized twice from ether pentane gave the title compound as tiny white clusters, m. 56°-58°.

Workup

  1. temperaturewas heated at 50° overnight
  2. extractionextracted with ether which
  3. dry with materialwas dried (NH2SO4)
  4. customevaporated
  5. dissolutionThe residue dissolved
  6. filtrationCH2Cl2 was filtered
  7. customevaporated
  8. customdried at 30°/0.5 mm

Sources & evidence

ORD record
ord-4f03c4f755164f668cb2aaa6dee356e0
Source dataset
uspto-grants-1993_08
Patent number
US05233063

Reaction notes

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