4-Bromobiphenyl → HCID 13392351, compound

Participants

Reaction Steps

In the same apparatus and procedures as Example 2-i) were reacted 18.7 g (80 mmol) of 4-bromobiphenyl, 4.8 g of magnesium and 0.7 g of iodine to prepare 4-phenylphenyl Grignard solution. In the same apparatus and procedures were reacted 10.4 ml (80 mmol) of chloromethyldimethylchlorosilane and the prepared 4-phenylphenyl Grignard solution to treat the reaction product. After separating them by using silica gel column (eluent: hexane), 12 g of chloromethyldimethyl(4-phenylphenyl)silane (92%) was obtained.

Provenance & Evidence