4-Bromobiphenyl → HCID 13392351, compound

HRID 2254312Notes

Reaction equation

HRID 2254312 reaction equation
Br[C:2]1[CH:7]=[CH:6][C:5]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)=[CH:4][CH:3]=1.[Mg].[Cl:15][CH2:16][Si:17]([CH3:20])([CH3:19])Cl>II>[Cl:15][CH2:16][Si:17]([CH3:20])([CH3:19])[C:2]1[CH:7]=[CH:6][C:5]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)=[CH:4][CH:3]=1

Participants

5

Reactant 3

HCID 71014-BromobiphenylHCID 74393Silane, chloro(chloromethyl)dimethyl-HCID 5462224Magnesium

Product 1

HCID 13392351HCID 13392351, compoundYield 92%

Reagents, catalysts & solvents 1

HCID 807IodineCatalyst

Procedure

In the same apparatus and procedures as Example 2-i) were reacted 18.7 g (80 mmol) of 4-bromobiphenyl, 4.8 g of magnesium and 0.7 g of iodine to prepare 4-phenylphenyl Grignard solution. In the same apparatus and procedures were reacted 10.4 ml (80 mmol) of chloromethyldimethylchlorosilane and the prepared 4-phenylphenyl Grignard solution to treat the reaction product. After separating them by using silica gel column (eluent: hexane), 12 g of chloromethyldimethyl(4-phenylphenyl)silane (92%) was obtained.

Workup

  1. customto prepare 4-phenylphenyl Grignard solution
  2. customAfter separating them

Sources & evidence

ORD record
ord-707820fced9f40a08b1b2ec15833ffc5
Source dataset
uspto-grants-1993_08
Patent number
US05235061

Reaction notes

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