Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Ethyl Acetate | HCID 8857 | — |
| Reactant | Hydroxyamine hydrochloride | HCID 443297 | — |
| Reactant | HCID 14739679 | HCID 14739679 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | HCID 86744614 | HCID 86744614 | 91.8% |
Reaction Steps
A mixture of 1.1 g of 2-(decyloxy)-5-[3(ethyloxycarbonyl)benzoyl]benzenepropanoic acid, ethyl ester and 220 mg of hydroxylamine hydrochloride in 25 ml of pyridine was heated at 70° C. for approximately 18 hours. The reaction was allowed to cool to ambient temperature, ethyl acetate was added, and the solution was washed several times with lN hydrochloric acid and water. The organic layer was dried over sodium sulfate and concentrated in vacuo to provide 1.04 g of the desired title product as an oil. NMR.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US05235064 |
|---|
| Source dataset | uspto-grants-1993_08 |
|---|
| ORD ID | ord-9a7e16007bc24b789879fb7a3a0dece8 |
|---|
| Source note | uspto-grants-1993_08 |
|---|
