2-Ethyl 2-(hydroxymethyl)hexanal → 2-Butyl-2-ethyl-1,3-propanediol

HRID 2254381Notes

Reaction equation

HRID 2254381 reaction equation
[CH2:1]([C:3]([CH2:10][OH:11])([CH2:6][CH2:7][CH2:8][CH3:9])[CH:4]=[O:5])[CH3:2]>[Ni]>[CH2:6]([C:3]([CH2:1][CH3:2])([CH2:4][OH:5])[CH2:10][OH:11])[CH2:7][CH2:8][CH3:9]

Participants

3

Reactant 1

HCID 125384672-Ethyl 2-(hydroxymethyl)hexanal

Product 1

HCID 610382-Butyl-2-ethyl-1,3-propanediol

Reagents, catalysts & solvents 1

HCID 935NickelCatalyst

Procedure

continuously feeding the organic phase of step (8) to a hydrogenation zone wherein the 2-ethyl-2-(hydroxymethyl)hexanal is contacted with a supported nickel hydrogenation catalyst at a total pressure of about 21 to 36 bars absolute and at a hydrogenation zone exit temperature of about 150° to 170° C. to produce 2-butyl-2-ethyl-1,3-propanediol.

Sources & evidence

ORD record
ord-bd8d90fd6d5f45d5b2c3730f4880a837
Source dataset
uspto-grants-1993_08
Patent number
US05235118

Reaction notes

Loading…