HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethyldioxirane → 1-Hydroxy-2,6-diphenyl-4-piperidone 1,2-Hexadecylene Ketal
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethyldioxirane | HCID 115197 | — |
| Reactant | 2,6-Diphenyl-4-piperidone 1,2-Hexadecylene Ketal | HCID 86747100 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 1-Hydroxy-2,6-diphenyl-4-piperidone 1,2-Hexadecylene Ketal | HCID 86747101 | 65% |
Reaction Steps
The general procedure of Example 2 is repeated using 10.9 g (22.2 mmol) of 2,6-diphenyl-4-piperidone 1,2-hexadecylene ketal and 376 mL (22.2 mmol) of dimethyldioxirane (0.059M in acetone). 7.3 g (65% yield) of the title compound is isolated as a white solid by recrystallization from ethanol: mp 98°-100° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05235056 |
| Source dataset | uspto-grants-1993_08 |
| ORD ID | ord-76c8d419e1384fdfac140a67c9cba29d |
| Source note | uspto-grants-1993_08 |