Triethylamine → HCID 19744464, compound

HRID 2254435Notes

Reaction equation

HRID 2254435 reaction equation
[CH3:1][O:2][CH:3]([O:14][CH3:15])[C:4]1[CH:9]=[CH:8][CH:7]=[C:6]([C:10](O)([CH3:12])[CH3:11])[CH:5]=1.CS(Cl)(=O)=O.C(N(CC)CC)C>C(Cl)Cl>[CH3:15][O:14][CH:3]([O:2][CH3:1])[C:4]1[CH:9]=[CH:8][CH:7]=[C:6]([C:10]([CH3:12])=[CH2:11])[CH:5]=1

Participants

5

Reactant 3

HCID 8471TriethylamineHCID 31297Methanesulfonyl chlorideHCID 19744477HCID 19744477, compound

Product 1

HCID 19744464HCID 19744464, compoundYield 95.7%

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

0.4 g of the alcohol compound obtained above was dissolved in 8 ml of purified methylene chloride, and with stirring under ice cooling, 0.24 g of methanesulfonyl chloride and 0.38 g of triethylamine were added. The mixture was stirred at room temperature for 2 hours. The reaction mixture was evaporatd under reduced pressure and then extracted by adding ethyl ether and water. The extract was worked up in a customary manner to give 0.35 g of crude 3-isopropenylbenzaldehyde dimethyl acetal as a pale yellow oil.

Workup

  1. stirringThe mixture was stirred at room temperature for 2 hours
  2. extractionextracted
  3. additionby adding ethyl ether and water

Sources & evidence

ORD record
ord-89ed5881aba4407fa0377a73d07f0861
Source dataset
uspto-grants-1993_08
Patent number
US05234946

Reaction notes

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