HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethylamine → (E)-N-(6,6-dimethyl-2-hepten-4-ynyl)-N-methyl-3-hydroxybenzylamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethylamine | HCID 6341 | — |
| Reactant | Propylamine | HCID 7852 | — |
| Reactant | (E)-N-(6,6-Dimethyl-2-hepten-4-ynyl)-N-ethyl-3-hydroxybenzylamine | HCID 10445905 | — |
| Reactant | 3-((Methylamino)methyl)phenol | HCID 10486905 | — |
| Reactant | (E)-N-(6,6-Dimethyl-2-hepten-4-ynyl)-N-propyl-3-hydroxybenzylamine | HCID 15290087 | — |
| Reactant | (E)-N-ethyl-N-(6-methoxy-6-methyl-2-hepten-4-ynyl)-3-hydroxybenzylamine | HCID 19744624 | — |
| Reactant | 1-Bromo-6-methoxy-6-methylhept-2-en-4-yne | HCID 53783202 | — |
| Reactant | Monomethylamine methanol | HCID 57454252 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | (E)-N-(6,6-dimethyl-2-hepten-4-ynyl)-N-methyl-3-hydroxybenzylamine | HCID 19916986 | — |
Reaction Steps
The 3-hydroxybenzylamine derivatives used in Examples 26 to 48, such as (E)-N-(6,6-dimethyl-2-hepten-4-ynyl)-N-ethyl-3-hydroxybenzylamine, (E)-N-(6,6-dimethyl-2-hepten-4-ynyl)-N-propyl-3-hydroxybenzylamine or (E)-N-ethyl-N-(6-methoxy-6-methyl-2-hepten-4-ynyl)-3-hydroxybenzylamine, were obtained by performing the same reaction as in Referential Example 26 except that in place of the starting methylamine-methanol solution, a methanol solution of ethylamine or propylamine was used and as required, 1-bromo-6-methoxy-6-methyl-2-hepten-4-yne was used instead of 1-bromo-6,6-dimethyl-2-hepten-4-yne was used.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05234946 |
| Source dataset | uspto-grants-1993_08 |
| ORD ID | ord-fa3c1194eab94af5aeb960275f79a869 |
| Source note | uspto-grants-1993_08 |