Potassium Carbonate → HCID 12966957, compound

HRID 2254551Notes

Reaction equation

HRID 2254551 reaction equation
C1(C2C=CC(C([O:13][C@@H:14]3[CH2:21][C@H:20]4[C@H:16]([CH2:17][C:18](=[O:22])[O:19]4)[C@H:15]3/[CH:23]=[CH:24]/[C@@H:25]([O:33][CH:34]3[CH2:39][CH2:38][CH2:37][CH2:36][O:35]3)[CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH3:32])=O)=CC=2)C=CC=CC=1.C(=O)([O-])[O-].[K+].[K+]>CO>[OH:13][C@@H:14]1[CH2:21][C@H:20]2[C@H:16]([CH2:17][C:18](=[O:22])[O:19]2)[C@H:15]1/[CH:23]=[CH:24]/[C@@H:25]([O:33][CH:34]1[CH2:39][CH2:38][CH2:37][CH2:36][O:35]1)[CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH3:32]

Participants

4

Reactant 2

HCID 11430Potassium CarbonateHCID 12966956HCID 12966956, compound

Product 1

HCID 12966957HCID 12966957, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

The tetrahydropyranyl ether (5) (5.03 g) was dissolved into a dry methanol (300 ml), into which potassium carbonate (1.49 g) was added, and stirred at room temperature for 6 hours. A crude compound obtained by a usual work-up was column-chromatographed to give the title compound (6). Yield: 3.25 g.

Workup

  1. additionwas added
  2. customA crude compound obtained by a usual work-up
  3. customwas column-chromatographed

Sources & evidence

ORD record
ord-237785758d504f848f7f9b2ca13ceb39
Source dataset
uspto-grants-1993_08
Patent number
US05236907

Reaction notes

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