HRID2254572

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID13691213

未命名化合物

结构：C#CCN(Cc1ccc2ncn(COC(=O)C(C)(C)C)c(=O)c2c1)c1ccc(C(=O)N[C@@H](CCC(=O)OCC)C(=O)OCC)cc1

HCID13691215

未命名化合物

结构：C#CCNc1ccc(C(=O)N[C@@H](CCC(=O)OCC)C(=O)OCC)c(F)c1

HCID14730572

未命名化合物

PRODUCTS

生成物

结构：C#CCN(Cc1ccc2ncn(COC(=O)C(C)(C)C)c(=O)c2c1)c1ccc(C(=O)N[C@@H](CCC(=O)OCC)C(=O)OCC)c(F)c1

HCID14730576

未命名化合物

PROCEDURE

实验过程

The compound was prepared from compound (9) in a similar manner to that for the preparation of compound (5) from compound (4) in Example 1 using the reagent quantities and conditions set out in Table A.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-873d4085b5224f0793c6920dff159445
来源数据集: uspto-grants-1993_08
DOI: 10.6084/m9.figshare.5104873.v1
专利: US05236927
来源说明: uspto-grants-1993_08

反应 SMILES

[F:1]C1C=C(NCC#C)C=CC=1C(N[C@H](C(OCC)=O)CCC(OCC)=O)=O.[O:28]=[C:29]1[C:38]2[C:33](=[CH:34][CH:35]=[C:36]([CH2:39][N:40]([CH2:63][C:64]#[CH:65])[C:41]3[CH:62]=[CH:61][C:44]([C:45]([NH:47][C@H:48]([C:56]([O:58][CH2:59][CH3:60])=[O:57])[CH2:49][CH2:50][C:51]([O:53][CH2:54][CH3:55])=[O:52])=[O:46])=[CH:43][CH:42]=3)[CH:37]=2)[N:32]=[CH:31][N:30]1[CH2:66][O:67][C:68](=[O:73])[C:69]([CH3:72])([CH3:71])[CH3:70].BrCC1C=C2C(=CC=1)N=CN(COC(=O)C(C)(C)C)C2=O>>[F:1][C:61]1[CH:62]=[C:41]([N:40]([CH2:63][C:64]#[CH:65])[CH2:39][C:36]2[CH:37]=[C:38]3[C:33](=[CH:34][CH:35]=2)[N:32]=[CH:31][N:30]([CH2:66][O:67][C:68](=[O:73])[C:69]([CH3:71])([CH3:70])[CH3:72])[C:29]3=[O:28])[CH:42]=[CH:43][C:44]=1[C:45]([NH:47][C@H:48]([C:56]([O:58][CH2:59][CH3:60])=[O:57])[CH2:49][CH2:50][C:51]([O:53][CH2:54][CH3:55])=[O:52])=[O:46]