HRID2254573

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：C#CCN(Cc1ccc2ncn(COC(=O)C(C)(C)C)c(=O)c2c1)c1ccc(C(=O)N[C@@H](CCC(=O)OCC)C(=O)OCC)cc1

HCID13691215

未命名化合物

结构：C#CCN(Cc1ccc2ncn(COC(=O)C(C)(C)C)c(=O)c2c1)c1ccc(C(=O)N[C@@H](CCC(=O)OCC)C(=O)OCC)c(F)c1

HCID14730576

未命名化合物

PRODUCTS

生成物

结构：C#CCN(Cc1ccc2nc[nH]c(=O)c2c1)c1ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)c(F)c1

HCID136035435

未命名化合物

PROCEDURE

实验过程

This compound was prepared from compound (10) in a similar manner to that for the preparation of CB 3804 from compound 5 in Example 1 using the reagent quantities and conditions set out in Table B.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-8e6055fa44d6425ea2652da54e6f9419
来源数据集: uspto-grants-1993_08
DOI: 10.6084/m9.figshare.5104873.v1
专利: US05236927
来源说明: uspto-grants-1993_08

反应 SMILES

[F:1][C:2]1[CH:23]=[C:22]([N:24]([CH2:45][C:46]#[CH:47])[CH2:25][C:26]2[CH:27]=[C:28]3[C:33](=[CH:34][CH:35]=2)[N:32]=[CH:31][N:30](COC(=O)C(C)(C)C)[C:29]3=[O:44])[CH:21]=[CH:20][C:3]=1[C:4]([NH:6][C@H:7]([C:15]([O:17]CC)=[O:16])[CH2:8][CH2:9][C:10]([O:12]CC)=[O:11])=[O:5].O=C1C2C(=CC=C(CN(CC#C)C3C=CC(C(N[C@H](C(OCC)=O)CCC(OCC)=O)=O)=CC=3)C=2)N=CN1COC(=O)C(C)(C)C>>[F:1][C:2]1[CH:23]=[C:22]([N:24]([CH2:45][C:46]#[CH:47])[CH2:25][C:26]2[CH:27]=[C:28]3[C:33](=[CH:34][CH:35]=2)[N:32]=[CH:31][NH:30][C:29]3=[O:44])[CH:21]=[CH:20][C:3]=1[C:4]([NH:6][C@H:7]([C:15]([OH:17])=[O:16])[CH2:8][CH2:9][C:10]([OH:12])=[O:11])=[O:5]