HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → HCID 178517531, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 3-[(4-Bromo-2,5-difluorobenzoyl)amino]thiophene-2-carboxamide | HCID 57753049 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 178517531 | HCID 178517531 | — |
Reaction Steps
A mixture of 3-[(4-bromo-2,5-difluorobenzoyl)amino]thiophene-2-carboxamide; 1M NaOH aq and MeOH was stirred for two hours at 80° C. to give 2-(4-bromo-2,5-difluorophenyl)thieno[3,2-d]pyrimidine-4(1H)-one.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07557112B2 |
| Source dataset | uspto-grants-2009_07 |
| ORD ID | ord-fa1daa4fe4a74a1ca37039c3c8f1a8fc |
| Source note | uspto-grants-2009_07 |