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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 225464Generated: October 30, 2026

Phosphorus oxychloride → HCID 57753077, compound

https://huagongshe.com/reaction/225464

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPhosphorus oxychlorideHCID 24813—
ReactantHCID 178517534HCID 178517534—
ProductHCID 57753077HCID 57753077—

Reaction Conditions

Temperature90 °C

Reaction Steps

A mixture of 2-(4-chloro-2,5-difluorophenyl)thieno[3,2-d]pyrimidine-4(1H)-one and phosphorus oxychloride was stirred for four hours at 90° C. to give 4-chloro-2-(4-chloro-2,5-difluorophenyl)thieno[3,2-d]pyrimidine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07557112B2
Source datasetuspto-grants-2009_07
ORD IDord-f1e93a1b59a64712a0691c7aeb14cd6f
Source noteuspto-grants-2009_07