Triethylamine → HCID 86615849, compound

HRID 225465Notes

Reaction equation

HRID 225465 reaction equation
C(N(CC)CC)C.[CH3:8][S:9](Cl)(=[O:11])=[O:10].[Cl:13][C:14]1[C:23]([Cl:24])=[CH:22][C:17]([C:18]([O:20][CH3:21])=[O:19])=[C:16]([C:25]2[NH:26][C:27](=[O:34])[C:28]3[S:33][CH:32]=[CH:31][C:29]=3[N:30]=2)[CH:15]=1>C(Cl)(Cl)Cl>[Cl:13][C:14]1[C:23]([Cl:24])=[CH:22][C:17]([C:18]([O:20][CH3:21])=[O:19])=[C:16]([C:25]2[N:26]=[C:27]([O:34][S:9]([CH3:8])(=[O:11])=[O:10])[C:28]3[S:33][CH:32]=[CH:31][C:29]=3[N:30]=2)[CH:15]=1

Participants

5

Reactant 3

HCID 8471TriethylamineHCID 31297Methanesulfonyl chlorideHCID 136330594Methyl 4,5-dichloro-2-(4-oxo-3,4-dihydrothieno[3,2-d]pyrimidine-2-yl)benzoate

Product 1

HCID 86615849HCID 86615849, compound

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

Triethylamine and methanesulfonyl chloride were added to a chloroform solution of methyl 4,5-dichloro-2-(4-oxo-3,4-dihydrothieno[3,2-d]pyrimidine-2-yl)benzoate under ice cooling and stirred under ice cooling for 30 minutes to give methyl 4,5-dichloro-2-{4-[(methanesulfonyl)oxy]thieno[3,2-d]pyrimidine-2-yl}benzoate.

Sources & evidence

ORD record
ord-e7549501cd1d4214af2ec9a458decd6a
Source dataset
uspto-grants-2009_07
Patent number
US07557112B2

Reaction notes

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