Benzoic acid, 2-amino-5-iodo- → HCID 135493457, compound

HRID 2255097Notes

Reaction equation

HRID 2255097 reaction equation
[N+]([C:4]1[CH:5]=[C:6]2[C:11](=[CH:12][CH:13]=1)[NH:10][C:9]([CH2:14][CH2:15][CH3:16])=[N:8][C:7]2=[O:17])([O-])=O.[I:18]C1C=C(C(O)=O)C(N)=CC=1>>[I:18][C:4]1[CH:5]=[C:6]2[C:11](=[CH:12][CH:13]=1)[N:10]=[C:9]([CH2:14][CH2:15][CH3:16])[NH:8][C:7]2=[O:17]

Participants

3

Reactant 2

HCID 72911Benzoic acid, 2-amino-5-iodo-HCID 178440202HCID 178440202, compound

Product 1

HCID 135493457HCID 135493457, compound

Procedure

Following the procedure described as in the preparation of 6-nitro-2-propylquinazolin-4(1H)-one above. 25 g of 5-iodoanthranilic acid was converted into the title compound. 1H-NMR (CDCl3, 200 MHz): δ1.02 (t, 3H, J=7.4 Hz), 1.81 (m, 2H), 2.63 (t, 2H, J=7.4 Hz), 7.40 (d, 1H, J=8.6 Hz), 8.07 (dd, 1H, J=2, 8.7 Hz).1H, J=8.6 Hz), 8.07 (dd, 1H, J=2, 8.7 Hz).

Sources & evidence

ORD record
ord-8a11361b84f54f71a4cc7d15cfa60f4a
Source dataset
uspto-grants-1993_08
Patent number
US05238942

Reaction notes

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