HCID 19741716, compound → HCID 178511452, compound

Participants

Reaction Steps

A solution of methyl α-[(phenylcarbonyl)amino]-3-[(phenylcarbonyl)-oxy]-4-[[2-(tributylstannyl)-1H-tetrazol-5-yl]methyl]benzeneacetate from the Preparation 11 above in 6N HCl is heated at reflux until consumed. The reaction mixture is cooled to room temperature and extracted with 1:1 ether/toluene. The aqueous phase is concentrated to give the product of α-amino-3-hydroxy-4-(1H-tetrazol-5-ylmethyl)-benzeneacetic acid.

Provenance & Evidence